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The First Test for the early detection of spontaneous premature birth in the Market

What is quantusPREMATURITY?

quantusPREMATURITY is an early detection test for spontaneous, robust, rapid and easy to use preterm birth that is based on the automatic analysis of an ultrasound image.

quantusPREMATURITY works through a web application. It is a platform in which you can upload the ultrasound of the cervix of which you want to know the risk of spontaneous preterm birth (before 34 and / or 37 weeks of gestation), as well as the subsequent reception of the results.

With an unprecedented solution, quantusPREMATURITY can provide reliable results in a few minutes.

quantusPREMATURITY provides an early detection alternative for predicting SPtB risk reliably; reaching levels of precision, performance and reproducibility unprecedented in the state of the art techniques based on the measurement of the Cervical Length (CL).

  sPTB risk < 34 gestational weeks sPTB < 37 gestational weeks
  CL quantusPREMATURITY CL quantusPREMATURITY
Sensitivity 10% 32.4% 10.3% 13.2%
Specificity 98.8% 99.5 99.1% 98.7%
PPV 10.0% 98.8% 95.7% 95.8%
NPV 98.4% 98.8% 95.7 95.8%

Why does quantusPREMATURITY work?

The changes that occur histologically in a tissue (collagen, fat or water ratio, among others) affect the way in which the ultrasound wave interferes in it, thus generating a different signal. Using advanced techniques of image processing in Artificial Intelligence, this signal difference can be analyzed quantitatively and therefore, detect small changes not visible to the human eye that give us more information about the state of the tissue.

The cervix is ​​a potential candidate for the application of this type of technology, since it must be remodeled microstructurally during pregnancy to prepare the moment of delivery. An early or premature remodeling of the cervix usually precedes the SPtB and inadequate softening can lead to a failed induction of labor. An early identification of a premature cervical remodeling process could reduce the possible maternal and perinatal complications associated with SPtB.

quantusPREMATURITY has been developed to be used as a universal screening tool in pregnant women of the general population regardless of cervical length. It may be useful for those patients with short cervical length who may present a low risk of spontaneous premature delivery, or with a normal cervical length and who are at high risk.

sPTB: Spontaneous Preterm Birth Basal risk quantusPREMATURITY Cervical Length <=25mm
High Risk Low Risk High Risk Low Risk
<34 weeks 1.7% 25.8% 1.1% 12.5% 1.5%
<37 weeks 4.8% 46.7% 4.1% 37.4% 4.3%

Why is quantusPREMATURITY different?

The current test based on cervical length is the default method for evaluating cervical remodeling associated with the risk of preterm birth. This technique has the following disadvantages:

Manual measurement
The measurement of CL is a process that can provide variability to the result
Little accurate
Very few cases experience changes in the cervical structure during the second trimester
No universal
It is not recommended for the entire population, it is considered only in cases of risk

quantusPREMATURITY provides an Efficient solution for the early detection of spontaneous preterm birth risk. Its features are: eficiente para la determinación temprana del riesgo de parto prematuro espontáneo. Sus características son:

Robust
The information obtained gives us variability.
Reliable
The detection of changes in the cervical microstructure is validated through scientific studies.
Universal
Recommended test for the general population, intended as a second-trimester screening test for all pregnant women

Offer better care with an economical solution. In three simple steps you will get an unlimited experience

Instant and around-the-clock services: As long as there is Internet, you can use quantusPREMATURITY and review the results anytime, anywhere.

No installation required: quantusPREMATURITY is designed to give new users an easy start because neither downloading nor installation of any software is required.

Great compatibility: quantusPREMATURITY is compatible with major web browsers as well as most commonly-used Obstetrics and Gynecology Ultrasound Machines.


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